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dc.contributor.advisor Mamdouh, Wael
dc.contributor.author James, Kegere
dc.date.accessioned 2016-05-15T07:38:05Z
dc.date.available 2018-05-15T22:00:14Z
dc.date.created Fall 2015 en_US
dc.date.issued 2016-05-15
dc.identifier.uri http://dar.aucegypt.edu/handle/10526/4705
dc.description.abstract Given the current Challenges faced by the increasing rate of drug resistant bacteria, a lot of attention has been shifted from synthetic antibiotic products to natural products that are eco friendly and have a wide spectrum of activity when exposed to pathogens. The main objective of this research was to successfully fabricate electrospun nanofibers from polyvinyl alcohol, polyvinyl alcohol blended with Chitosan, Bidens pilosa (Both distilled and crude extract) composite blends and invesitigate their potential antibacterial activities agains E. coli and S. aureus. Fabrication of nanofibers was performed by the electrospinner technique which applies high voltage on the polymer forcing it to spinnoff as a spray onto a collector. Characterization of the nanofibers was successfully performed by Scanning electron microscopy (SEM), Fourier Transform infrared (FT-IR) spectroscopy technique. To study anti bacterial effect, E.coli and S. aureus were cultured in Luria Broth liquid media for 24 hrs at 37 °C after which nanofibers from different composite blends were exposed to the bacteria in three well plate. Hourly measurements of optical density using a spectophotometer were carried out. Results obtained show enhanced antibacterial activity of composite nanofibers obtained from combinations containing either crude extract or Chitosan. Whereas Chitosan nanofibers are already well researched and its anti microbial property vastly known, Bidens pilosa although known to possess biomedical properties, its anti bacterial properties in nanofiber form have not been reported in literature. en_US
dc.description.sponsorship African Graduate Fellowship AUC. en_US
dc.format.extent 116 p. en_US
dc.format.medium theses en_US
dc.language.iso en en_US
dc.rights Author retains all rights with regard to copyright. en
dc.subject Nanocomposites en_US
dc.subject.lcsh Thesis (M.S.)--American University in Cairo en_US
dc.title Fabrication of polyvinyl alcohol / chitosan / bidens pilosa composite electrospun nanofibers and their enhanced antibacterial activities en_US
dc.type Text en_US
dc.subject.discipline Nanotechnology en_US
dc.rights.access This item is restricted for 2 years from the date issued en_US
dc.contributor.department American University in Cairo. Yousef Jameel Science and Technology Research Center en_US
dc.description.irb American University in Cairo Institutional Review Board approval has been obtained for this item. en_US
dc.contributor.committeeMember El Sayed, Mayyada, Medhat Al Ghobashy


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  • Theses and Dissertations [1728]
    This collection includes theses and dissertations authored by American University in Cairo graduate students.

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