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dc.contributor.advisor Tamer Shoeib, Gihan El Moghazy Abubakr, Rahma 2017-09-14T09:09:21Z Fall 2017 en_US 2017-09-14
dc.description.abstract Mycotoxins are natural toxins produced by fungus. These toxins are food and feed contaminants inducing diverse toxicological effects on human and animal health that may affect different organs. These adverse effects may be hepatotoxic, nephrotoxic and neurotoxic; these effects may be acute or chronic implying that even traces amount of mycotoxins, may accumulate over time and become problematic. The occurrence of mycotoxins in food and feed are thus an issue of critical importance and is of main concern worldwide. Among the efforts that are being made to limits mycotoxins occurrence in food are the laws and regulations on their permissible limits. For instance, the permissible limits of Aflatoxins in peanuts are 4 ng/g for total aflatoxins and 2 ng/g for aflatoxin B1. These limits and regulations are based on human risk assessment studies, data about the occurrence of mycotoxins in various commodities, and the availability of sensitive and accurate analytical methods for their determination. In this work we developed a rapid, selective, sensitive, accurate and validated method for the simultaneous quantification of aflatoxins using LC-ESI-MS/MS. The developed method was applied on different sample matrices; peanuts (n = 45), lentils (n = 10), beans (n = 3), and wheat (n =2). The first ever reported data on the occurrence and levels of aflatoxins in peanuts in Greater Cairo are presented. The results presented here show that the investigated peanuts samples from 5 different regions in Greater Cairo contain mean concentrations of total aflatoxin ranging from 16.69 to 101.93 ng/g which are 4 to 25.5 times higher than the permissible limits set by the European Union and FDA. en_US
dc.description.sponsorship American University in Cairo And The Regional Center for Food and Feed, Agriculture Research Center. en_US
dc.format.extent 65 p. en_US
dc.format.medium theses en_US
dc.language.iso en en_US
dc.rights Author retains all rights with regard to copyright. en
dc.subject Mycotoxins en_US
dc.subject Aflatoxins en_US
dc.subject LC- MS/MS and Peanuts en_US
dc.subject.lcsh Thesis (M.S.)--American University in Cairo en_US
dc.title Mycotoxins detection in grains and nuts using LC – MS/MS en_US
dc.type Text en_US
dc.subject.discipline Chemistry en_US
dc.rights.access This item is restricted for 2 years from the date issued en_US
dc.contributor.department American University in Cairo. Dept. of Chemistry en_US
dc.embargo.lift 2019-09-14T09:09:21Z
dc.description.irb American University in Cairo Institutional Review Board approval is not necessary for this item, since the research is not concerned with living human beings or bodily tissue samples. en_US
dc.contributor.committeeMember Ramadan, Adham
dc.contributor.committeeMember Abdel Ghani, Nour Eldin

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  • Theses and Dissertations [1521]
    This collection includes theses and dissertations authored by American University in Cairo graduate students.

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